Article
RsgA releases RbfA from 30S ribosome during a late stage of ribosome biosynthesis.
The EMBO journal - 5 Jan 2011
Goto Simon, Kato Shingo, Kimura Takatsugu, Muto Akira, Himeno Hyouta
Abstract excerpt
RsgA is a 30S ribosomal subunit-binding GTPase with an unknown function, shortage of which impairs maturation of the 30S subunit. We identified multiple gain-of-function mutants of Escherichia coli rbfA, the gene for a ribosome-binding factor, that suppress defects in growth and maturation of the 30S subunit of an rsgA-null strain. These mutations promote spontaneous release of RbfA from the 30S subunit,...
Topics
- Escherichia coli
- Escherichia coli Proteins
- GTP Phosphohydrolases
- Mutation
- Protein Binding
- Ribosomal Proteins
- Ribosome Subunits, Small, Bacterial
- Ribosomes