Article
[Proliferative activity and defective replication in breast cancer].
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 1994
Kreipe H, Zeidler R, Kneitz H, Feist H
Abstract excerpt
The highly proliferating phenotype of mammary carcinoma is known to be associated with a particularly aggressive clinical course. We have been interested in the underlying molecular causes that give rise to the increased proliferative activity Proliferative activity was determined immunohistochem...
Topics
- Breast Neoplasms
- Cell Cycle
- Cell Division
- DNA Replication
- DNA Topoisomerases, Type II
- Female
- Gene Amplification
- Genes, p53
- Humans
- Immunohistochemistry
- Phenotype