Article
Generation of immunostimulatory dendritic cells from human CD34+ hematopoietic progenitor cells of the bone marrow and peripheral blood.
Cancer research - 1 Mar 1995
Bernhard H, Disis M L, Heimfeld S, Hand S, Gralow J R, Cheever M A
Abstract excerpt
Dendritic antigen-presenting cells are considered to be the most effective stimulators of T cell immunity. The use of dendritic cells has been proposed to generate therapeutic T cell responses to tumor antigens in cancer patients. One limitation is that the number of dendritic cells in peripheral...
Topics
- Antigen Presentation
- Antigens, CD
- Antigens, CD34
- B7-1 Antigen
- Bone Marrow
- Bone Marrow Cells
- Cells, Cultured
- Dendritic Cells
- Granulocyte-Macrophage Colony-Stimulating Factor
- Hematopoietic Stem Cells
- Histocompatibility Antigens Class II
- Humans
- Leukocytes, Mononuclear
- Lymphocyte Activation
- Macrophages
- Peptide Fragments
- Phenotype
- Receptor, ErbB-2