Article
p-nitrosophenol reduction by liver cytosol from ADH-positive and -negative deermice (Peromyscus maniculatus).
Archives of biochemistry and biophysics - 1 Feb 1995
Dudley B F, Winston G W
Abstract excerpt
Liver cytosolic fractions are known to catalyze the reduction of certain C-nitroso compounds to their corresponding hydroxylamines and amines. Alcohol dehydrogenase (ADH), NAD(P)H:quinone oxidoreductase, and xanthine and aldehyde oxidases have been implicated as C-nitroso reductases. To probe the role of these cytosolic enzymes in the reduction of C-nitroso compounds we have studied the effects of classical...
Topics
- Alcohol Dehydrogenase
- Aldehyde Oxidase
- Aldehyde Oxidoreductases
- Aminophenols
- Animals
- Animals, Laboratory
- Cytosol
- Dicumarol
- Liver
- Mutation
- NAD
- NAD(P)H Dehydrogenase (Quinone)