Ethanol oxidation by deermice mitochondria under physiologic conditions.

doi:10.1111/j.1530-0277.1990.tb00460.x

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Article

Ethanol oxidation by deermice mitochondria under physiologic conditions.

Alcoholism, clinical and experimental research - 1 Feb 1990

Inatomi N, Ito D, Lieber C S

Abstract excerpt

Mitochondria obtained from alcohol dehydrogenase-positive or - negative deermice do not oxidize significant amounts of ethanol at pH 7.4. A slight activity, equivalent to less than 0.3% of the elimination rate in alcohol dehydrogenase-negative deermice was observed at pH 10; it was strongly inhib...

Topics

Alcohol Dehydrogenase
Animals
Cytosol
Ethanol
Genotype
In Vitro Techniques
Kinetics
Microsomes, Liver
Mitochondria, Liver
NAD
Oxidation-Reduction
Peromyscus

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