Article
Human immunodeficiency virus type 2 (HIV-2) env gene analysis: prediction of glycoprotein epitopes important for heterotypic neutralization and evidence for three genotype clusters within the HIV-2a subtype.
The Journal of general virology - 1 Feb 1995
Breuer J, Douglas N W, Goldman N, Daniels R S
Abstract excerpt
The env gene sequences of ten tissue-culture-adapted human immunodeficiency virus type 2 (HIV-2) isolates from West African patients were determined. Alignment and comparison of the gene sequences and putative translation products with database sequences revealed 11-29% diversity at the nucleotide level and 15-31% variation at the protein level. From analysis of glycoproteins of HIV-2 strains sensitive and...
Topics
- Amino Acid Sequence
- Base Sequence
- Epitopes
- Genes, env
- Genotype
- HIV Envelope Protein gp120
- HIV Envelope Protein gp41
- HIV-2
- Humans
- Immune Sera
- Molecular Sequence Data