Article
Evolution of the tenascin family--implications for function of the C-terminal fibrinogen-like domain.
Perspectives on developmental neurobiology - 1 Jan 1994
Erickson H P
Abstract excerpt
The three members of the tenascin (TN) family, TN-C, TN-R, and TN-X, are apparently conserved in all vertebrates and therefore must have functions that contribute to survival. One specific domain of tenascins, the fibrinogen-like terminal knob, can be argued to have an essential function. Its pos...
Topics
- Animals
- Cell Adhesion Molecules, Neuronal
- Extracellular Matrix Proteins
- Fibrinogen
- Growth Substances
- Humans
- Mice
- Mice, Knockout
- Molecular Sequence Data
- Multigene Family
- Mutation
- Phylogeny
- Protein Structure, Tertiary
- Sequence Homology, Amino Acid
- Species Specificity
- Structure-Activity Relationship
- Tenascin
- Time Factors