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Article

Tenascin-X: beyond the architectural function

2 Jan 2015

Abstract excerpt

Tenascin-X is the largest member of the tenascin (TN) family of evolutionary conserved extracellular matrix glycoproteins, which also comprises TN-C, TN-R and TN-W. Among this family, TN-X is the only member described so far to exert a crucial architectural function as evidenced by a connective tissue disorder (a recessive form of Ehlers-Danlos syndrome) resulting from a loss-of-function of this glycoprotein in...

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PMID: 25793578
DOI: 10.4161/19336918.2014.994893

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