Long-term treatment of canine cyclic hematopoiesis with recombinant canine stem cell factor.

Abstract excerpt

Grey collie dogs have cyclic fluctuations in their blood cell counts caused by a regulatory defect of hematopoietic stem cells. To examine the role of stem cell factor (SCF) or its receptor in this disorder, we investigated the stimulatory effects of recombinant canine SCF (rc-SCF) on in vitro marrow cultures, cloned and sequenced the grey collie SCF gene, and treated three grey collies with rc-SCF, either alone...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Macrophages
• Share to Molecular Sequence Data
• Share to Base Sequence