Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diverse isoforms of colony-stimulating factor-1 have different effects on the development of stroma-dependent hematopoietic cells.

Journal of cellular physiology - 1 Jul 2005

Friel Jutta, Heberlein Christoph, Geldmacher Maren, Ostertag Wolfram

Abstract excerpt

Maintenance and differentiation of hematopoietic stem and progenitor cells are controlled by complex interactions with the stroma microenvironment. Stroma-cell interactions can be supported by locally expressed membrane-spanning cell-surface (cs) growth factors. CSF-1 is expressed by stroma as a soluble glycoprotein, as proteoglycan, or as a membrane-spanning cs glycoprotein. CSF-1 regulates the survival,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD34
Share to Antigens, Ly

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Isomerism

Share to Macrophage Colony-Stimulating Factor

Share to Proteoglycans

Share to Retroviridae

Share to Stromal Cells

Share to Transduction, Genetic

Source

Identifiers

PMID: 15744782
DOI: 10.1002/jcp.20291

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diverse isoforms of colony-stimulating factor-1 have different effects on the development of stroma-dependent hematopoietic cells.PMID 15744782Read ↗

Hierarchy of stroma-derived factors in supporting growth of stroma-dependent hemopoietic cells: membrane-bound SCF is sufficient to confer stroma competence to epithelial cells.Semantic proximity Read ↗

Developmental and functional significance of the CSF-1 proteoglycan chondroitin sulfate chain.Semantic proximity Read ↗

Support of human hematopoiesis in long-term bone marrow cultures by murine stromal cells selectively expressing the membrane-bound and secreted forms of the human homolog of the steel gene product, stem cell factor.Semantic proximity Read ↗

Engineered niches support the development of human dendritic cells in humanized miceSemantic proximity Read ↗

The biology and action of colony stimulating factor-1.Semantic proximity Read ↗

A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells.Semantic proximity Read ↗

Distinct hematopoietic support by two human stromal cell lines.Semantic proximity Read ↗

Phenotype and function of stromal cells cloned from the ileal Peyer's patch of sheep.Semantic proximity Read ↗

Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors.Semantic proximity Read ↗

Early growth response 1 regulates hematopoietic support and proliferation in human primary bone marrow stromal cellsSemantic proximity Read ↗

Rescue of the colony-stimulating factor 1 (CSF-1)-nullizygous mouse (Csf1(op)/Csf1(op)) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis.Semantic proximity Read ↗

The presence of novel amino acids in the cytoplasmic domain of stem cell factor results in hematopoietic defects in Steel(17H) mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.