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Article

Recombinant human stem cell factor, a c-kit ligand, stimulates hematopoiesis in primates.

Blood - 15 Oct 1991

Andrews R G, Knitter G H, Bartelmez S H, Langley K E, Farrar D, Hendren R W, Appelbaum F R, Bernstein I D, Zsebo K M

Abstract excerpt

Recombinant human stem cell factor (SCF) is homologous with recombinant rat SCF (rrSCF) and is a ligand for c-kit. We determined the influence of SCF on hematopoiesis in vitro and in vivo in baboons. In vitro, SCF alone stimulated little growth of hematopoietic colony-forming cells from baboon marrow, but did increase the number of colonies formed in response to erythropoietin (Epo), interleukin-3 (IL-3), and...

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PMID: 1912579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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