Article
Recombinant human stem cell factor, a c-kit ligand, stimulates hematopoiesis in primates.
Blood - 15 Oct 1991
Andrews R G, Knitter G H, Bartelmez S H, Langley K E, Farrar D, Hendren R W, Appelbaum F R, Bernstein I D, Zsebo K M
Abstract excerpt
Recombinant human stem cell factor (SCF) is homologous with recombinant rat SCF (rrSCF) and is a ligand for c-kit. We determined the influence of SCF on hematopoiesis in vitro and in vivo in baboons. In vitro, SCF alone stimulated little growth of hematopoietic colony-forming cells from baboon ma...
Topics
- Animals
- Bone Marrow Cells
- Hematopoiesis
- Hematopoietic Cell Growth Factors
- Papio
- Phenotype
- Recombinant Proteins