Direct measurement of the influenza A virus M2 protein ion channel activity in mammalian cells.

doi:10.1006/viro.1994.1628

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Article

Direct measurement of the influenza A virus M2 protein ion channel activity in mammalian cells.

Virology - 15 Nov 1994

Wang C, Lamb R A, Pinto L H

Abstract excerpt

The influenza A virus M2 integral membrane protein has an ion channel activity which is thought to play an essential role in the uncoating process of influenza virus in infected cells and, for some strains of influenza virus, in maintaining the hemagglutinin in its pH neutral form during transpor...

Topics

Amantadine
Animals
Blotting, Western
Cells, Cultured
Fluorescent Antibody Technique
Hydrogen-Ion Concentration
Influenza A virus
Ion Channels
Mammals
Membrane Potentials
Mutation
Viral Matrix Proteins

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