Structural features of keratin intermediate filaments.

doi:10.1111/1523-1747.ep12398900

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Article

Structural features of keratin intermediate filaments.

The Journal of investigative dermatology - 1 Nov 1994

Steinert P M, North A C, Parry D A

Abstract excerpt

The first step in the assembly of a keratin intermediate filament (KIF) is the formation of a type I/type II heterodimer molecule in which two chains become aligned in parallel and close axial registration to form a flexible segmented alpha-helical coiled-coil rope 46 nm long. The segments of coi...

Topics

Amino Acid Sequence
Animals
Genetic Linkage
Humans
Intermediate Filaments
Keratins
Models, Molecular
Models, Structural
Molecular Sequence Data
Multigene Family
Mutation
Skin Diseases

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