Article
Structural features of keratin intermediate filaments.
The Journal of investigative dermatology - 1 Nov 1994
Steinert P M, North A C, Parry D A
Abstract excerpt
The first step in the assembly of a keratin intermediate filament (KIF) is the formation of a type I/type II heterodimer molecule in which two chains become aligned in parallel and close axial registration to form a flexible segmented alpha-helical coiled-coil rope 46 nm long. The segments of coiled-coil are interspersed by sequences that introduce irregularities of unknown structure. Here we have modeled two of...
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