Genetic skin diseases caused by mutations in keratin intermediate filaments.

doi:10.1016/0168-9525(93)90014-9

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Article

Genetic skin diseases caused by mutations in keratin intermediate filaments.

Trends in genetics : TIG - 1 Aug 1993

Steinert P M, Bale S J

Abstract excerpt

Keratin intermediate filaments are the major differentiation products of epithelial cells such as the epidermis. The filaments are highly dynamic entities involved in the maintenance of the structural integrity of both the individual cells and the entire tissue. Recent biochemical studies suggest...

Topics

Amino Acid Sequence
Animals
Humans
Intermediate Filaments
Keratins
Molecular Sequence Data
Mutation
Skin Diseases

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