Article
Reduced numbers of CD8+ T cells and B cell-expression of Leu-8 antigen in peripheral blood of patients with primary biliary cirrhosis.
Hepato-gastroenterology - 1 Jun 1994
Moreno-Otero R, Civeira M P, Suou T, Kanof M E, James S P, Jones E A
Abstract excerpt
The presence of Leu-8 antigen, the human homologue of the murine MEL-14 peripheral lymph node homing receptor, defines subsets of peripheral blood mononuclear cells (PBMC) with different functions. Since it has been suggested that abnormal function of Leu-8 subsets may contribute to the immunopat...
Topics
- Adult
- Aged
- Antibodies, Monoclonal
- Antigens, CD
- Antigens, CD19
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocyte Subsets
- B-Lymphocytes
- Bilirubin
- Biomarkers
- CD4-CD8 Ratio
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Case-Control Studies
- Cell Adhesion Molecules
- Cell Division
- Female
- Flow Cytometry