Article
The Drosophila orb RNA-binding protein is required for the formation of the egg chamber and establishment of polarity.
Genes & development - 1 Mar 1994
Lantz V, Chang J S, Horabin J I, Bopp D, Schedl P
Abstract excerpt
The orb gene of Drosophila encodes sex-specific germ-line proteins that contain two RRM-type RNA-binding domains. Here we report the distribution of Orb protein in wild-type, tumorous, and orb mutant ovaries. The wild-type distribution of Orb protein during oogenesis resembles that of its RNA, preferentially accumulating in the cytoplasm of the developing oocyte shortly after the formation of the 16-cell cyst. As...
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