Article
Identification and analysis of mutations in bob, Doa and eight new genes required for oocyte specification and development in Drosophila melanogaster.
Genetics - 1 Aug 2003
Morris Jason Z, Navarro Caryn, Lehmann Ruth
Abstract excerpt
The Drosophila oocyte develops from a cluster of 16 interconnected cells that derive from a common progenitor. One of these cells, the oocyte, arrests in meiosis. The other cells endoreplicate their DNA and produce mRNAs and proteins that they traffic to the oocyte along a polarized microtubule cytoskeleton shared by the entire cyst. Therefore, Drosophila oogenesis is an attractive system for the study of cell...
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