Article
Reactions of Ugandan antisera with peptides encoded by V3 loop epitopes of human immunodeficiency virus type 1.
AIDS research and human retroviruses - 1 May 1994
Smith J D, Bruce C B, Featherstone A S, Downing R G, Biryahawaho B, Clegg J C, Carswell J W, Oram J D
Abstract excerpt
The specificities of antibodies reacting with peptides encoded by V3 loop apical epitopes were determined for sera from 230 seropositive Ugandans, including asymptomatic persons and AIDS patients, sampled between 1986 and 1992. Most (71%) of the sera reacted with the peptide encoded by HIV-MN, 59...
Topics
- Adult
- Amino Acid Sequence
- Antibody Specificity
- Binding, Competitive
- Consensus Sequence
- Epitopes
- Female
- Genetic Variation
- HIV Antibodies
- HIV Envelope Protein gp120
- HIV Infections
- HIV-1
- Humans
- Molecular Sequence Data
- Peptide Fragments
- Uganda
