Article
Antisera raised against the second variable region of the external envelope glycoprotein of human immunodeficiency virus type 1 cross-neutralize and show an increased neutralization index when they act together with antisera to the V3 neutralization epitope.
The Journal of general virology - 1 Dec 1993
Davis D, Stephens D M, Carne C A, Lachmann P J
Abstract excerpt
Antibodies have been raised against a synthetic peptide (IRDKIQKENALFRNL) containing a neutralizing epitope within the second variable region of the human immunodeficiency virus type 1 (HIV-1) SF2 strain external envelope glycoprotein (gp120) and also against equivalent peptides of the HIV-1 LAI,...
Topics
- Amino Acid Sequence
- Animals
- Cells, Cultured
- Cross Reactions
- Drug Synergism
- Epitopes
- Genetic Variation
- HIV Antibodies
- HIV Envelope Protein gp120
- HIV Seropositivity
- HIV-1
- Humans
- Molecular Sequence Data
- Neutralization Tests