Article
Involvement of CD44 and its variant isoforms in membrane-cytoskeleton interaction, cell adhesion and tumor metastasis.
Journal of neuro-oncology - 1 Dec 1995
Bourrguignon L Y, Iida N, Welsh C F, Zhu D, Krongrad A, Pasquale D
Abstract excerpt
CD44s (standard form of CD44) is a transmembrane glycoprotein whose external domain displays extracellular matrix adhesion properties by binding both hyaluronic acid (HA) and collagen. The cytoplasmic domain of CD44s interacts with the cytoskeleton by binding directly to ankyrin. It has been show...
Topics
- Animals
- Ankyrins
- Breast Neoplasms
- Carcinoma
- Cell Adhesion
- Cell Membrane
- Cytoskeleton
- Female
- Gene Expression
- Genetic Variation
- Humans
- Hyaluronan Receptors
- Male
- Neoplasm Metastasis
- Neoplasms
- Polymerase Chain Reaction
- Prostatic Neoplasms
- Protein Processing, Post-Translational