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Article

Involvement of CD44 and its variant isoforms in membrane-cytoskeleton interaction, cell adhesion and tumor metastasis.

Journal of neuro-oncology - 1 Dec 1995

Bourrguignon L Y, Iida N, Welsh C F, Zhu D, Krongrad A, Pasquale D

Abstract excerpt

CD44s (standard form of CD44) is a transmembrane glycoprotein whose external domain displays extracellular matrix adhesion properties by binding both hyaluronic acid (HA) and collagen. The cytoplasmic domain of CD44s interacts with the cytoskeleton by binding directly to ankyrin. It has been shown that post-translational modifications, such as phosphorylation (by protein kinase C), acylation (by acyl-transferase)...

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Source

Identifiers

PMID: 8750186
DOI: 10.1007/BF01052623

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Involvement of CD44 and its variant isoforms in membrane-cytoskeleton interaction, cell adhesion and tumor metastasis.PMID 8750186Read ↗

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CD44: A Multifunctional Cell Surface Adhesion Receptor Is a Regulator of Progression and Metastasis of Cancer CellsSemantic proximity Read ↗

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Expression and modulation of CD44 variant isoforms in humansSemantic proximity Read ↗

Current status of CD44 variant isoforms as cancer diagnostic markers.Semantic proximity Read ↗

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Novel variants of CD44 arising from alternative splicing: changes in the CD44 alternative splicing pattern of MCF-7 breast carcinoma cells treated with hyaluronidase.Semantic proximity Read ↗

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