Alternative splicing of CD44 pre-mRNA in human colorectal tumors.

doi:10.1006/bbrc.1994.1551

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Article

Alternative splicing of CD44 pre-mRNA in human colorectal tumors.

Biochemical and biophysical research communications - 29 Apr 1994

Finn L, Dougherty G, Finley G, Meisler A, Becich M, Cooper D L

Abstract excerpt

Expression of the CD44 molecule has been linked to tumor growth and metastases in both human and rodent cancers. Alternatively spliced variants expressed in rat and mouse tumors have been shown to confer metastatic potential to non-metastatic carcinoma cell lines, and human homologues of rat variant mRNA sequences are expressed in human tumors. In the present study matched sets of RNA from adenocarcinomas of the...

Topics

Adenocarcinoma
Alternative Splicing
Animals
Base Sequence
Carrier Proteins
Colorectal Neoplasms
DNA Primers
DNA, Neoplasm
Exons
Gene Amplification
Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Variation

Humans

Hyaluronan Receptors

Molecular Sequence Data

Prognosis

RNA Precursors

RNA, Neoplasm

Source

Open in PubMed

Identifiers

PMID: 7513991
DOI: 10.1006/bbrc.1994.1551

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7513991-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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