Article
Alternative splicing of CD44 pre-mRNA in human colorectal tumors.
Biochemical and biophysical research communications - 29 Apr 1994
Finn L, Dougherty G, Finley G, Meisler A, Becich M, Cooper D L
Abstract excerpt
Expression of the CD44 molecule has been linked to tumor growth and metastases in both human and rodent cancers. Alternatively spliced variants expressed in rat and mouse tumors have been shown to confer metastatic potential to non-metastatic carcinoma cell lines, and human homologues of rat variant mRNA sequences are expressed in human tumors. In the present study matched sets of RNA from adenocarcinomas of the...
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