Article
Ratio of CD44 epithelial variant to CD44 hematopoietic variant is a useful prognostic indicator in gastric and colorectal carcinoma.
Japanese journal of clinical oncology - 1 Oct 1998
Shibuya Y, Okabayashi T, Oda K, Tanaka N
Abstract excerpt
BACKGROUND: The CD44 is a cell adhesion molecule that is present as numerous isoforms created by mRNA alternative splicing. Expression of variant isoforms of CD44 is associated with tumor growth and metastasis. The aim of this study was to evaluate whether CD44 isoform expression is a prognostic...
Topics
- Adult
- Aged
- Aged, 80 and over
- Colorectal Neoplasms
- Epithelium
- Genetic Variation
- Hematopoietic System
- Humans
- Hyaluronan Receptors
- Middle Aged
- Neoplasm Invasiveness
- Prognosis
- RNA, Messenger
- Reverse Transcriptase Polymerase Chain Reaction
- Stomach Neoplasms
