Clonal proliferation of Langerhans cells in Langerhans cell histiocytosis.

doi:10.1016/s0140-6736(94)91842-2

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Article

Clonal proliferation of Langerhans cells in Langerhans cell histiocytosis.

Lancet (London, England) - 26 Mar 1994

Yu R C, Chu C, Buluwela L, Chu A C

Abstract excerpt

X-chromosome-inactivation assays can be used to assess clonality. We used such an assay at the human androgen-receptor gene locus in three female patients with histologically proven Langerhans cell histiocytosis. All patients were heterozygous for this locus. Cells bearing the Langerhans cell phenotype were purified from involved tissue after fluorescence-activated cell sorting with monoclonal antibodies against...

Topics

Antibodies, Monoclonal
Antigens, CD
Antigens, CD1
Base Sequence
Cell Division
Child, Preschool
Clone Cells
Dosage Compensation, Genetic
Electrophoresis, Polyacrylamide Gel
Female
Flow Cytometry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Histiocytosis, Langerhans-Cell

Humans

Infant

Langerhans Cells

Molecular Sequence Data

Phenotype

Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 7510816
DOI: 10.1016/s0140-6736(94)91842-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7510816-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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