In situ detection of activated cytotoxic cells in follicular lymphomas.

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Article

In situ detection of activated cytotoxic cells in follicular lymphomas.

The American journal of pathology - 1 Mar 1994

Leger-Ravet M B, Devergne O, Peuchmaur M, Solal-Celigny P, Brousse N, Gaulard P, Galanaud P, Emilie D

Abstract excerpt

The presence of cytotoxic cells and their activation status were analyzed in tissue sections of 26 follicular lymphomas. To this end, expression of the perforin and granzyme B genes was studied by in situ hybridization experiments, and expression of the TIA-1 antigen was analyzed by immunohistochemistry. Cells expressing the granzyme B gene and the perforin gene were detected in all cases. Their density was,...

Topics

Adult
Aged
Aged, 80 and over
Antigens, CD
Antigens, Differentiation, B-Lymphocyte
Antigens, Differentiation, T-Lymphocyte
CD4 Antigens
CD56 Antigen
CD8 Antigens
Cell Adhesion Molecules
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression Regulation, Neoplastic

Granzymes

Humans

Immunohistochemistry

In Situ Hybridization

Lectins

Lymphocyte Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 7510456
PMCID: PMC1887084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7510456-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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