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Article

Evaluation of the cytotoxic response mediated by perforin and granzyme B in patients with non-Hodgkin lymphoma.

Leukemia & lymphoma - 1 Jan 2018

Souza Bruna Maria Bereta, De Vito Fernanda Bernadelli, Calado Marianna Licati, Silva Marcos Vinícius, Oliveira Leonardo Rodrigues, Rodrigues-Júnior Virmondes, Moraes-Souza Helio

Abstract excerpt

This study quantified the perforin and granzyme B in patients with non-Hodgkin lymphoma (NHL) at the time of diagnosis. Protein quantification was performed by flow cytometry. NHL patients had a higher number of cytotoxic T lymphocytes (CTLs) expressing perforin as well as a greater number of activated CTLs than the control group. However, intracellular perforin levels in natural killer cells were lower in the...

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Share to Aged, 80 and over
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Killer Cells, Natural

Share to Lymphoma, Non-Hodgkin

Share to Perforin

Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 28679297
DOI: 10.1080/10428194.2017.1341978

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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