The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis.

doi:10.1006/viro.1994.1151

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Article

The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis.

Virology - 1 Mar 1994

Lee S B, Esteban M

Abstract excerpt

Interferons (IFNs) exert antitumor activities, but the molecular mechanism underlying these effects is poorly understood. IFN-induced, double-stranded (ds) RNA-activated protein kinase (p68 kinase) has long been implicated in mediating the antiproliferative effects of IFN. In addition, recent stu...

Topics

Apoptosis
HeLa Cells
Humans
Interferons
Mutation
Protein Serine-Threonine Kinases
Recombinant Proteins
Vaccinia virus
eIF-2 Kinase

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