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Article

Rearrangement of the VP6 gene of a group A rotavirus in combination with a point mutation affecting trimer stability

1 Mar 1994

Abstract excerpt

A group A rotavirus isolated from a lamb with diarrhea in Qinhai province, China, was serially passaged in fetal calf kidney cells. In passage 96, rearrangements of RNA segments 5 and 6 of the viral genome were found. Here we report the nucleotide and predicted amino acid sequences of normal and rearranged RNA 6, coding for the major inner capsid protein VP6. In comparison with the normal gene (N6), the...

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PMID: 7509001
DOI: 10.1128/jvi.68.3.1682-1688.1994

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