Article
No correlation between DNA strand breaks and HPRT mutation induced by photochemical treatment in V79 cells.
Mutation research - 1 Jan 2000
Noodt B B, Moan J, Kvam E, Steen H B
Abstract excerpt
DNA strand breaks, measured by alkaline elution, and hypoxanthine guanine phosphoribosyltransferase (HPRT) mutation were studied in V79 cells after photochemical treatment (PCT) or exposure to X-rays. Cells were incubated with the photosensitizers Photofrin II (PII) and three closely related porphyrins tetra-(3-hydroxyphenyl) porphyrin (3THPP), meso-tetra-(4-sulfonatophenyl) porphine (TPPS4) and...
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