No correlation between DNA strand breaks and HPRT mutation induced by photochemical treatment in V79 cells.

doi:10.1016/0165-7992(94)90048-5

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Article

No correlation between DNA strand breaks and HPRT mutation induced by photochemical treatment in V79 cells.

Mutation research - 1 Jan 2000

Noodt B B, Moan J, Kvam E, Steen H B

Abstract excerpt

DNA strand breaks, measured by alkaline elution, and hypoxanthine guanine phosphoribosyltransferase (HPRT) mutation were studied in V79 cells after photochemical treatment (PCT) or exposure to X-rays. Cells were incubated with the photosensitizers Photofrin II (PII) and three closely related porp...

Topics

Animals
Cells, Cultured
Cricetinae
DNA
DNA Damage
DNA Repair
Hypoxanthine Phosphoribosyltransferase
Light
Mutation
Photosensitizing Agents
Porphyrins
X-Rays

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