International Commission for Protection Against Environmental Mutagens and Carcinogens. Working paper no. 5. Impact of the molecular spectrum of mutational lesions on estimates of germinal gene-mutation rates.

Abstract excerpt

Review of the molecular characteristics of the variants identified at a series of disease loci suggests significant differences among loci in the relative frequency of nucleotide substitutions versus more complex events such as deletions. Some common features are repeatedly observed in each class...

Topics

• Deoxyribonucleotides
• Gene Deletion
• Gene Frequency
• Genetic Variation
• Mutagenesis