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Article

The extent of amyloid deposition in brain in patients with Down's syndrome does not depend upon the apolipoprotein E genotype.

Neuroscience letters - 18 Aug 1995

Mann D M, Pickering-Brown S M, Siddons M A, Iwatsubo T, Ihara Y, Asami-Odaka A, Suzuki N

Abstract excerpt

The extent of deposition of amyloid beta protein (A beta) was investigated in 20 elderly patients with Down's syndrome, using the end-specific monoclonal antibodies BC05 and BA27 to detect the presence of A beta 42(43) and A beta 40 (respectively), and related to apolipoprotein E (ApoE) genotype. No significant differences in the amount of A beta deposited in the brain, either as A beta 42(43) or A beta 40, were...

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Source

Identifiers

PMID: 7501233
DOI: 10.1016/0304-3940(95)11860-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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