Article
Plasma beta-amyloid and duration of Alzheimer's disease in adults with Down syndrome.
International journal of geriatric psychiatry - 1 Feb 2010
Prasher V P, Sajith S G, Mehta P, Zigman W B, Schupf N
Abstract excerpt
OBJECTIVES: To investigate the relation of plasma levels of Abeta peptides (Abeta1-40 and Abeta1-42) and apolipoprotein E (APOE) genotype to dementia status, and the duration of Alzheimer's disease (AD) in adults with Down syndrome (DS). METHODS: Adults with DS were recruited from community settings and followed up for a mean period of 6.7 years. Plasma levels Abeta1-40 and Abeta1-42 and APOE genotype were...
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