Article
Regulation of protein secretion into bile: studies in mice with a disrupted mdr2 p-glycoprotein gene.
Gastroenterology - 1 Dec 1995
Groen A K, Van Wijland M J, Frederiks W M, Smit J J, Schinkel A H, Oude Elferink R P
Abstract excerpt
BACKGROUND & AIMS: Protein is secreted into bile via several independent pathways. The aim of this study was to investigate whether these pathways are influenced by secretion of biliary lipid. METHODS: Protein secretion and biliary lipid output were studied in wild-type mice (+/+), heterozygotes...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- Alkaline Phosphatase
- Animals
- Bile
- CD13 Antigens
- Cholagogues and Choleretics
- Enzyme-Linked Immunosorbent Assay
- Genes
- Lipid Metabolism
- Mice
- Mice, Transgenic
- Mutation
- Phospholipids
- Proteins
- Taurochenodeoxycholic Acid
- Taurocholic Acid