Article
Absence of mutations in superoxide dismutase and catalase genes in patients with Parkinson's disease.
Archives of neurology - 1 Dec 1995
Parboosingh J S, Rousseau M, Rogan F, Amit Z, Chertkow H, Johnson W G, Manganaro F, Schipper H N, Curran T J, Stoessl J
Abstract excerpt
BACKGROUND: Parkinson's disease (PD) is an adult-onset, neurodegenerative disorder characterized by a selective loss of the dopaminergic cells of the substantia nigra and by progressive motor decline. Studies have shown aberrant oxidative stress metabolism within the substantia nigra and other dopaminergic regions of the brain in patients with PD. OBJECTIVE: To screen the genes of three free radical detoxifying...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.