Absence of mutations in superoxide dismutase and catalase genes in patients with Parkinson's disease.

doi:10.1001/archneur.1995.00540360038013

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Article

Absence of mutations in superoxide dismutase and catalase genes in patients with Parkinson's disease.

Archives of neurology - 1 Dec 1995

Parboosingh J S, Rousseau M, Rogan F, Amit Z, Chertkow H, Johnson W G, Manganaro F, Schipper H N, Curran T J, Stoessl J

Abstract excerpt

BACKGROUND: Parkinson's disease (PD) is an adult-onset, neurodegenerative disorder characterized by a selective loss of the dopaminergic cells of the substantia nigra and by progressive motor decline. Studies have shown aberrant oxidative stress metabolism within the substantia nigra and other do...

Topics

Adult
Aged
Catalase
Female
Humans
Male
Middle Aged
Mutation
Parkinson Disease
Polymorphism, Single-Stranded Conformational
Superoxide Dismutase

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