Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Strategies for pharmacologic modulation of the heart failure phenotype.

Clinical cardiology - 1 Sept 1995

Feldman A M, McNamara D M, Rosenblum W D, Murali S

Abstract excerpt

The end-stage heart failure phenotype is characterized by marked dyspnea on exertion, edema, and overwhelming fatigue, and by a high incidence of sudden death. Patients who display the end-stage phenotype have transitioned from a normal phenotype with myocardial damage at a cellular level. This t...

Topics

Adrenergic beta-Antagonists
Angiotensin-Converting Enzyme Inhibitors
Cytokines
Heart Failure
Humans
Phenotype
Renin-Angiotensin System

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7489618
DOI: 10.1002/clc.4960181606

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7489618-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Strategies for pharmacologic modulation of the heart failure phenotype.PMID 7489618Read ↗

Mechanisms of current therapeutic strategies for heart failure: more questions than answers?Semantic proximity Read ↗

Biological Phenotypes of Heart Failure With Preserved Ejection Fraction.Semantic proximity Read ↗

Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction: A Multiorgan Roadmap.Semantic proximity Read ↗

New strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes.Semantic proximity Read ↗

The cardiac enigma: current conundrums in heart failure researchSemantic proximity Read ↗

Heart failure with preserved ejection fraction: Classification based upon phenotype is essential for diagnosis and treatment.Semantic proximity Read ↗

Heart Failure with Preserved Ejection Fraction: The Pathophysiological Mechanisms behind the Clinical Phenotypes and the Therapeutic Approach.Semantic proximity Read ↗

Heart Failure with Reduced and Mildly Reduced Ejection Fraction: A Network Interpretive Framework of Mechanisms, Phenotypes, and Therapeutic Response.Semantic proximity Read ↗

Phenotype-guided approach for device-based therapies in heart failure.Semantic proximity Read ↗

Cardiac rehabilitation in heart failure: Indications for exercise training based on heart failure phenotype.Semantic proximity Read ↗

β₃-Adrenergic Signaling in Heart Failure: A Stage-Dependent Double-Edged SwordSemantic proximity Read ↗

New Management Strategies in Heart Failure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.