Mapping of the serotonin 5-HT1D beta autoreceptor gene on chromosome 6 and direct analysis for sequence variants.

doi:10.1002/ajmg.1320600214

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Article

Mapping of the serotonin 5-HT1D beta autoreceptor gene on chromosome 6 and direct analysis for sequence variants.

American journal of medical genetics - 24 Apr 1995

Lappalainen J, Dean M, Charbonneau L, Virkkunen M, Linnoila M, Goldman D

Abstract excerpt

Abnormal brain serotonin function may be characteristic of several neuropsychiatric disorders. Thus, it is important to identify polymorphic genes and screen for functional variants at loci coding for genes that control normal serotonin functions. 5-HT1D beta is a terminal serotonin autoreceptor which may play a role in regulating serotonin synthesis and release. Using an SSCP technique we screened for 5-HT1D...

Topics

Alcoholism
Base Sequence
Brain
Chromosome Mapping
Chromosomes, Human, Pair 6
DNA Primers
Genetic Linkage
Genetic Markers
Genetic Variation
Humans
Hydroxyindoleacetic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Molecular Sequence Data

Polymerase Chain Reaction

Polymorphism, Single-Stranded Conformational

Receptor, Serotonin, 5-HT1B

Receptors, Serotonin

Source

Open in PubMed

Identifiers

PMID: 7485252
DOI: 10.1002/ajmg.1320600214

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7485252-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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