Exclusion of linkage between alcoholism and the MNS blood group region on chromosome 4q in multiplex families.

doi:10.1002/ajmg.1320600113

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Article

Exclusion of linkage between alcoholism and the MNS blood group region on chromosome 4q in multiplex families.

American journal of medical genetics - 27 Feb 1995

Neiswanger K, Kaplan B, Hill S Y

Abstract excerpt

Polymorphic DNA markers on the long arm of chromosome 4 were used to examine linkage to alcoholism in 20 multiplex pedigrees. Fifteen loci were determined for 124 individuals. Lod scores were calculated assuming both dominant and recessive disease modes of inheritance, utilizing incidence data by...

Topics

Alcoholism
Chromosome Mapping
Chromosomes, Human, Pair 4
DNA
Female
Genes, Recessive
Genetic Linkage
Genetic Markers
Humans
Lod Score
MNSs Blood-Group System
Male
Pedigree
Phenotype

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