Article
Exclusion of linkage between alcoholism and the MNS blood group region on chromosome 4q in multiplex families.
American journal of medical genetics - 27 Feb 1995
Neiswanger K, Kaplan B, Hill S Y
Abstract excerpt
Polymorphic DNA markers on the long arm of chromosome 4 were used to examine linkage to alcoholism in 20 multiplex pedigrees. Fifteen loci were determined for 124 individuals. Lod scores were calculated assuming both dominant and recessive disease modes of inheritance, utilizing incidence data by age and gender that allow for correction for variable age of onset and frequency of the disorder by gender. Under the...
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