Article
Sex-based linkage analysis of alcoholism.
Genetic epidemiology - 1 Jan 1999
Paterson A D, Petronis A
Abstract excerpt
A high degree of locus heterogeneity is likely in alcoholism, and linkage heterogeneity analysis may be helpful in mapping susceptibility loci. The genetic contribution to alcoholism in females may be higher than in males, and therefore sex of affected individuals was used in linkage analysis. Families with female alcoholics demonstrated evidence for linkage to chromosomes 10p11-p15 and 21q22.1-q22.2 while those...
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