Article
Linkage of an alcoholism-related severity phenotype to chromosome 16.
Alcoholism, clinical and experimental research - 1 Dec 1998
Foroud T, Bucholz K K, Edenberg H J, Goate A, Neuman R J, Porjesz B, Koller D L, Rice J, Reich T, Bierut L J, Cloninger C R, Nurnberger J I, Li T K, Conneally P M, Tischfield J A, Crowe R, Hesselbrock V, Schuckit M, Begleiter H
Abstract excerpt
There is substantial evidence for a significant genetic component to the risk for alcoholism. In searching for genes that contribute to this risk, the diagnostic criteria for alcohol dependence may not be the optimal phenotype; rather, creation of a more homogeneous phenotype will lead to a more...
Topics
- Adult
- Alcohol Withdrawal Delirium
- Alcoholism
- Alleles
- Chromosomes, Human, Pair 16
- Female
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Models, Genetic
- Phenotype