Article
Structural basis for serpin inhibitor activity.
Proteins - 1 Jul 1995
Wright H T, Scarsdale J N
Abstract excerpt
The mechanism of formation and the structures of serpin-inhibitor complexes are not completely understood, despite detailed knowledge of the structures of a number of cleaved and uncleaved inhibitor, noninhibitor, and latent serpins. It has been proposed from comparison of inhibitor and noninhibitor serpins in the cleaved and uncleaved forms that insertion of strand s4A into preexisting beta-sheet A is a...
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