Structural basis for serpin inhibitor activity.

doi:10.1002/prot.340220303

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Article

Structural basis for serpin inhibitor activity.

Proteins - 1 Jul 1995

Wright H T, Scarsdale J N

Abstract excerpt

The mechanism of formation and the structures of serpin-inhibitor complexes are not completely understood, despite detailed knowledge of the structures of a number of cleaved and uncleaved inhibitor, noninhibitor, and latent serpins. It has been proposed from comparison of inhibitor and noninhibi...

Topics

Amino Acid Sequence
Binding Sites
Computer Graphics
Hydrogen Bonding
Models, Chemical
Models, Molecular
Molecular Sequence Data
Mutation
Plasminogen Activator Inhibitor 1
Protein Binding
Protein Structure, Secondary
Serine Endopeptidases
Serine Proteinase Inhibitors
Serpins
alpha 1-Antitrypsin
alpha-2-Antiplasmin

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