Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ultraviolet B irradiation-induced G2 cell cycle arrest in human keratinocytes by inhibitory phosphorylation of the cdc2 cell cycle kinase.

Oncogene - 16 Nov 1995

Herzinger T, Funk J O, Hillmer K, Eick D, Wolf D A, Kind P

Abstract excerpt

In response to genotoxic stress, cell cycle progression can be arrested at certain checkpoints which serve to maintain genomic integrity. We have investigated the mechanism of ultraviolet B (UVB) irradiation-induced cell cycle arrest in normal human keratinocytes and in the HaCaT keratinocyte cell line which carries mutant p53 tumour suppressor protein. While only normal keratinocytes showed a delay in G1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle
Share to Cells, Cultured
Share to Cyclins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Phosphorylation

Share to Tumor Suppressor Protein p53

Share to Tyrosine

Share to Ultraviolet Rays

Source

Identifiers

PMID: 7478536

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ultraviolet B irradiation-induced G2 cell cycle arrest in human keratinocytes by inhibitory phosphorylation of the cdc2 cell cycle kinase.PMID 7478536Read ↗

Mechanism of ultraviolet B-induced cell cycle arrest in G2/M phase in immortalized skin keratinocytes with defective p53.Semantic proximity Read ↗

G2 phase cell cycle arrest in human skin following UV irradiationSemantic proximity Read ↗

Genotoxic-activated G2-M checkpoint exit is dependent on CDC25B phosphatase expressionSemantic proximity Read ↗

Human Embryonic Stem Cells Are Capable of Executing G1/S Checkpoint ActivationSemantic proximity Read ↗

Molecular Basis for G2 Arrest Induced by 2′- C -Cyano-2′-Deoxy-1-β- d - Arabino -Pentofuranosylcytosine and Consequences of Checkpoint AbrogationSemantic proximity Read ↗

p53-dependent G2 arrest associated with a decrease in cyclins A2 and B1 levels in a human carcinoma cell line.Semantic proximity Read ↗

Unconventional effects of UVA radiation on cell cycle progression in S. pombe.Semantic proximity Read ↗

Cell cycle kinetics following UVA irradiation in comparison to UVB and UVC irradiation.Semantic proximity Read ↗

Kinetics of nuclear phosphorylation ( -H2AX) in human lymphocytes treated in vitro with UVB, bleomycin and mitomycin CSemantic proximity Read ↗

Mechanisms of checkpoint kinase Rad53 inactivation after a double-strand break in Saccharomyces cerevisiae.Semantic proximity Read ↗

[Degradation of Cdc25A phosphatase in HeLa cells under normal and stress conditions].Semantic proximity Read ↗

Distinct Chk2 Activation Pathways Are Triggered by Genistein and DNA-damaging Agents in Human Melanoma CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.