Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Use of antibiotics to select auxotrophic mutants of Neisseria meningitidis.

Microbial pathogenesis - 1 Apr 1995

Erwin A L, Gill M J, Gotschlich E C

Abstract excerpt

Antibiotic selection of auxotrophs has been a powerful tool in the elucidation of bacterial metabolic pathways, but it has been difficult to adapt this method to Neisseria spp. We describe a procedure by which a population of mutagenized N. meningitidis is enriched for mutants with specific growth phenotypes. These experiments used a simple defined medium (modified from that described in J Bacteriol 1962; 83:...

Topics

Anti-Bacterial Agents
Cell Division
Mutation
Neisseria meningitidis

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7476094
DOI: 10.1016/s0882-4010(05)80005-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7476094-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Use of antibiotics to select auxotrophic mutants of Neisseria meningitidis.PMID 7476094Read ↗

Identification and characterization of auxotrophs of Neisseria meningitidis produced by Tn916 mutagenesis.Semantic proximity Read ↗

A Neisseria meningitidis fbpABC mutant is incapable of using nonheme iron for growth.Semantic proximity Read ↗

Isolation of Candida tropicalis auxotrophic mutants.Semantic proximity Read ↗

Inhibition of Streptococcus mutans by the antibiotic streptozotocin: mechanisms of uptake and the selection of carbohydrate-negative mutants.Semantic proximity Read ↗

Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen.Semantic proximity Read ↗

A large genomic island allows N eisseria meningitidis to utilize propionic acid, with implications for colonization of the human nasopharynxSemantic proximity Read ↗

Construction of a complete set of <i>Neisseria meningitidis</i> defined mutants – the NeMeSys 2.0 collection – and its use for the phenotypic profiling of the genome of an important human pathogenSemantic proximity Read ↗

The Host-Pathogen Interactions and Epicellular Lifestyle of Neisseria meningitidisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.