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Article

A Neisseria meningitidis fbpABC mutant is incapable of using nonheme iron for growth.

Infection and immunity - 1 May 1998

Khun H H, Kirby S D, Lee B C

Abstract excerpt

The neisserial fbpABC locus has been proposed to act as an iron-specific ABC transporter system. To confirm this assigned function, we constructed an fbpABC mutant in Neisseria meningitidis by insertional inactivation of fbpABC with a selectable antibiotic marker. The mutant was unable to use iron supplied from human transferrin, human lactoferrin, or iron chelates. However, the use of iron from heme and human...

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Identifiers

PMID: 9573125
DOI: 10.1128/IAI.66.5.2330-2336.1998
PMCID: PMC108199

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