New mouse dw allele: genetic location and effects on lifespan and growth hormone levels.

Abstract excerpt

We have reported the finding of a new mutation at the dwarf locus, named dwarf-J, gene symbol dwJ, in the C3H/HeJ inbred mouse strain. The C3H/HeJ-dwJ/dwJ mice are like DW/J-dw/dw mice in that both homozygotes are virtually devoid of GH in either pituitary glands or serum. Lifespan of dwJ/dwJ mice was not reduced. Linkage experiments designed to assign the dw gene, together with another gene weaver (wv), were...

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