Article
New mouse dw allele: genetic location and effects on lifespan and growth hormone levels.
The Journal of heredity - 1 Jan 2000
Eicher E M, Beamer W G
Abstract excerpt
We have reported the finding of a new mutation at the dwarf locus, named dwarf-J, gene symbol dwJ, in the C3H/HeJ inbred mouse strain. The C3H/HeJ-dwJ/dwJ mice are like DW/J-dw/dw mice in that both homozygotes are virtually devoid of GH in either pituitary glands or serum. Lifespan of dwJ/dwJ mic...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Dwarfism
- Electrophoresis, Polyacrylamide Gel
- Genes, Recessive
- Growth Hormone
- Life Expectancy
- Mice
- Mice, Inbred C3H
- Pituitary Gland
- Radioimmunoassay
