Article
The pharmacokinetics of acebutolol in man, following the oral administration of acebutolol HCl as a single dose (400 mg), and during and after repeated oral dosing (400 mg, b.d.).
Biopharmaceutics & drug disposition - 1 Jan 2000
Gulaid A A, James I M, Kaye C M, Lewellen O R, Roberts E, Sankey M, Smith J, Templeton R, Thomas R J
Abstract excerpt
The pharmacokinetics of acebutolol have been studied in eight healthy male volunteers following the oral administration of acebutolol hydrochloride ('Sectral', May & Baker) as a single dose (400 mg), and during and after repeated oral dosing (400 mg, b.d. for 56 days). Following single dose admin...
Topics
- Acebutolol
- Acetylation
- Adult
- Biotransformation
- Half-Life
- Humans
- Kinetics
- Male
- Phenotype
- Time Factors