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Article

Disposition and mass balance of [14C]vernakalant after single intravenous and oral doses in healthy volunteers.

Drug metabolism letters - 1 Apr 2011

Mao Z L, Alak A, Wheeler J J, Keirns J

Abstract excerpt

Vernakalant hydrochloride is a novel antiarrhythmic drug for the rapid conversion of atrial fibrillation to sinus rhythm and prevention of relapse. In this open-label, parallel design study, 8 healthy men received single 240-mg doses of [(14)C]vernakalant hydrochloride, given as a 10-minute intravenous (IV) infusion on day 1, and as an oral gel capsule on day 22. Plasma, urine, and fecal samples were collected...

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Source

Identifiers

PMID: 21457140
DOI: 10.2174/187231211795305249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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