Article
SCE, X-radiation sensitivity and mutation rate in multiple sclerosis.
Mutation research - 1 Jan 2000
Seshadri R, Sutherland G R, Baker E, Kutlaca R, Wigmore D, Morley A A
Abstract excerpt
In order to detect any underlying DNA abnormality that may be present in multiple sclerosis (MS), the incidence of SCE, X-radiation sensitivity and the frequency of 6-thioguanine-resistant cells were determined in the lymphocytes of 34 MS patients. As a group, MS patients showed an increase in the SCE rate compared to control. However, there was no increase in X-radiation sensitivity. The frequency of...
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