Article
SCE, X-radiation sensitivity and mutation rate in multiple sclerosis.
Mutation research - 1 Jan 2000
Seshadri R, Sutherland G R, Baker E, Kutlaca R, Wigmore D, Morley A A
Abstract excerpt
In order to detect any underlying DNA abnormality that may be present in multiple sclerosis (MS), the incidence of SCE, X-radiation sensitivity and the frequency of 6-thioguanine-resistant cells were determined in the lymphocytes of 34 MS patients. As a group, MS patients showed an increase in th...
Topics
- Crossing Over, Genetic
- Drug Resistance
- Humans
- Lymphocytes
- Multiple Sclerosis
- Mutation
- Sister Chromatid Exchange
- Thioguanine
- X-Rays