Mutation rate: some biological and biochemical considerations.

doi:10.1016/s0300-9084(82)80089-8

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Article

Mutation rate: some biological and biochemical considerations.

Biochimie - 1 Jan 2000

Echols H

Abstract excerpt

This article discusses ideas about the ways in which the high fidelity of DNA replication is achieved: base selection, exonucleolytic editing, and postreplicative proofreading. I also review possible mechanisms for the enhanced mutation rate associated with SOS induction. The concept of environme...

Topics

Base Composition
DNA Repair
DNA Replication
DNA-Directed DNA Polymerase
Escherichia coli
Genes
Mutation
T-Phages

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