Article
Passive protection against heterologous gram-negative bacteria mediated by antiserum to epimeraseless Rc mutant of Salmonella minnesota.
Annales d'immunologie - 1 Jan 2000
Konstantinov G, Karacholeva M, Eskenazy M, Ivanova R, Vassileva J, Naumova F, Tekelieva R, Strahilov D
Abstract excerpt
Antiserum to the epimeraseless Rc mutant of Salmonella minnesota was prepared by immunization of rabbits. The antiserum provided good protection in mice i.p. challenged with 125 and 25 LD50 doses of live heterologous Gram-negative bacteria i. e. S. typhimurium, Escherichia coli and Pseudomonas aeruginosa. The protection against Klebsiella pneumoniae was negligible. Pre-immune rabbit serum produced only marginal...
Topics
- Animals
- Escherichia coli Infections
- Female
- Immune Sera
- Immunization, Passive
- Klebsiella Infections
- Lethal Dose 50
- Male
- Mice
- Mutation
- Pseudomonas Infections