Article
The effect of dietary ascorbic acid and alpha-tocopherol on fecal mutagenicity.
Mutation research - 1 Jan 2000
Dion P W, Bright-See E B, Smith C C, Bruce W R
Abstract excerpt
The effect of supplemental ascorbic acid and alpha-tocopherol on fecal mutagenicity was examined in 2 studies involving 20 healthy human donors aged 22-55 years. The vitamins were given at a dose of 400 mg daily each. The mutagen was extracted from individual frozen feces samples with dichloromethane, and assayed with Salmonella Typhimurium tester strain TA100 without microsomal activation. In the first study,...
Topics
- Adult
- Ascorbic Acid
- Feces
- Female
- Humans
- Male
- Middle Aged
- Mutagenicity Tests
- Mutagens
- Mutation
- Salmonella typhimurium
- Vitamin E