Article
A new H-2-linked class I gene whose expression depends on a maternally inherited factor.
Nature - 1 Jan 2000
Lindahl K F, Hausmann B, Chapman V M
Abstract excerpt
The maternally transmitted antigen (Mta) is expressed on the cells of most strains of mice. It is a medial histocompatibility antigen, that is, it is recognized by unrestricted cytotoxic T lymphocytes as are major H antigens, but unlike these it is a weak transplantation antigen and does not itself restrict the T-cell recognition of minor H antigens. All other medial H antigens are encoded by genes closely linked...
Topics
- Alleles
- Animals
- Cytoplasm
- Gene Expression Regulation
- Genetic Linkage
- H-2 Antigens
- Histocompatibility Antigens
- Major Histocompatibility Complex
- Mice